宫颈细胞学涂片筛查宫颈病变895例临床分析

THE CLINICAL ANALYSIS OF UTERINE CERVICAL SMEAR DETECTION ON 895 CASES SCREENING CERVICAL LESIONS

目的分析895例宫颈细胞学涂片结果临床特点。方法 895例患者纳入观察。采用液基薄层细胞检测系统(Thinprep Cytology Test,TCT)对宫颈病变进行检测,疾病诊断以组织学病理诊断为标准。结果 895例病例中,宫颈脱落细胞学涂片检查发现异常32例,检出率3.57%。其中不典型鳞状上皮细胞和腺细胞(ASC-US,AGc-US)17例,占总检出病例的53.1%;不除外高度鳞状上皮病变不典型鳞状细胞(ASC-H)3例,占总检出病例的9.4%;低度鳞状上皮内病变(LSIL)7例,占总检出病例的21.8%,高度鳞状上皮内病变(HSIL)3例,占总检出病例的9.4%,鳞状细胞癌(SCC)2例,占总检出病例的6.3%。各年龄段数据行率的两两比较(多重比较)(Scheffe法),p>0.05。且经比较,TCT与病理活检的符合率较高。结论宫颈细胞学涂片检查能有效的发现早期宫颈恶性病变,建议30～60岁妇女应每年进行1次宫颈细胞学检查。

Objective To analyze the results of 895 cases of uterine cervical smear detection. Methods 895 patients were included in observation.Using Thinprep Cytology Test for cervical lesions,make pathological diagnosis according to the standard. Results Among 895 cases,the uterine cervical smear detection revealed abnormalities in 32 cases,the detection rate of 3.57%.In which atypical squamous cells（ASC-US/AGc-US） 17 cases,53.1% of total detected cases;atypical squamous cells,not excepting the high-grade squamous intraepithelial lesion（ASC-H） 3 cases,9.4% of the total cases detected;low-grade squamous intraepithelial lesion（LSIL） 7 cases,21.8% of total detected cases,high grade squamous intraepithelial lesion（HSIL） 3 cases,9.4% of total detected cases.Squamous cell carcinoma（SCC） 2 cases,6.3% of total detected cases.By means of rows of all ages get the rate of pairwise comparisons（multiple comparisons）（Scheffe method）,p0.05.And by comparison,TCT in line with the biopsy higher rate of. Conclusion Uterine cervical smear detection can effectively detect early malignant cervical lesions,we recommend that women aged 30～60 should be detected by cervical cytology per year.