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原发性高血压患者血清胱抑素与超敏C反应蛋白含量分析

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摘要 目的探讨原发性高血压患者血清胱抑素与超敏C反应蛋白含量在不同血压情况下的变化。方法取原发性高血压患者120例,1级患者、2级患者、3级患者各40例,检测其血清胱抑素和超敏C反应蛋白含量,组间进行比较,并与健康对照组作比较。结果原发性高血压各组患者血清胱抑素和超敏C反应蛋白含量与健康对照组比较,均明显增高,有显著差异。组间比较,随血压级别升高,血清胱抑素和超敏C反应蛋白含量均同步升高。对于血清胱抑素,高血压1级与2级之间、2级与3级之间比较,P<0.05,1级与3级之间P<0.01。对于hsCRP,高血压1级与2级之间、2级与3级之间、1级与3级之间均P<0.01。结论原发性高血压患者具有明显增高的血清胱抑素和超敏C反应蛋白水平,二者与高血压的发生强烈相关,且二者有明显相关性,推测二者均与高血压发生的血管炎症和损伤因素有关,血清胱抑素对超敏C反应蛋白具有促进作用。推测对血压进行合理管理达到有效控制则可明显降低血清胱抑素和超敏C反应蛋白水平。
出处 《中国老年保健医学》 2011年第6期10-11,共2页 Chinese Journal of Geriatric Care
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