液基薄层细胞学检测技术在宫颈病变诊断中的应用价值

The Application of Liquid Cytology for Detection Technology in the Diagnosis of Cervical Lesions

目的探讨液基薄层细胞学(TCT)检测技术在宫颈病变诊断中的应用价值。方法对我院2011年3～6月妇产科门诊及住院患者3105例TCT检查结果进行回顾性分析。结果 198例为宫颈不同阶段病变,占6.38%,合并细菌性阴道病185例,占5.96%;非典型鳞状细胞,意义不明确(ASC-US)124例,占3.99%;非典型鳞状细胞,不除外高级别鳞状细胞上皮病变(ASC-H)27例,占0.87%;低级别鳞状上皮内病变(LSIL)10例,占0.32%;高级别鳞状上皮内病变(HSIL)8例,占0.26%;鳞状细胞癌(SCC)4例,占0.13%;乳头状瘤病毒感染(HPV)25例,占0.81%。TCT检测异常的22例做了组织学对照,其诊断符合率为90.91%。结论 TCT对宫颈病变的阳性检出率和诊断准确率高,是宫颈病变首选的筛查方法。

Objective To explore the application of liquid cytology for detection technology in the diagnosis of cervical lesions.Methods 3105 cases in gynecologic clinics and inpatients during March and June 2011 underwent TCT examination,and the results were retrospectively reviewed.Results 198 cases were detected with various cervical lesions（6.38%）;185 patients were detected with bacterial vaginal disease（5.96%）;124 cases were detected with ASC-US（3.99%）;27 cases were detected with ASC-H（0.87%）;10 cases were detected with LSIL（0.32%）;8 cases were detected with HSIL（0.26%）;4 cases were detected with squamous carcinoma（0.13%）;25 cases were detected with HPV infection（0.81%）.22 cases of TCT abnormality underwent biopsy for control,and the diagnosis accuracy rate was 90.91%.Conclusion TCT has a high accuracy rate in the positive detection and diagnosis in cervical lesions,and should be the first choice in detecting cervical lesions.