安徽省北部疟疾流行区中华按蚊溴氰菊酯抗性现状

Investigation of Anopheles sinensis resistance to deltamethrin in the malaria-endemic northern part of Anhui Province,China

目的探明安徽省北部疟疾流行区中华按蚊的溴氰菊酯抗性现状。方法选择涡阳县临湖镇、蒙城县坛城镇、太和县大新镇、利辛县纪五场乡,每乡镇各选取1个自然村,于2011年7～8月采用牛诱和猪诱法捕获饱血中华按蚊,采用WHO推荐的成蚊接触筒法进行按蚊敏感性测试。结果涡阳县临湖镇,蒙城县坛城镇、太和县大新镇、利辛县纪五场乡捕获的中华按蚊0.05%溴氰菊酯击倒率分别为2.73%、4.9%、4.72%和6.42%,校正死亡率分别为6.54%、7.78%、9.27%和11.18%,均为抗性群体。结论安徽省北部疟疾流行区中华按蚊已经对溴氰菊酯产生明显抗性。

Objective To determine the resistance of Anopheles sinensis to deltamethrin in the malaria-endemic northern part of Anhui Province. Methods An.sinensis adults were collected in pig-and cow-baited traps in July and August 2011.Standards assays recommended by the WHO were used to test F0 generation females.Mortality was recorded 24 hours after exposure. Results An.sinensis from Guoyang,Mencheng,Taihe,and Lixin counties was knocked down with 0.05% deltamethrin at a rate of 2.73%,4.9%,4.72%,and 6.42%,respectively.And with mortality were 6.54%,7.78%,9.27%,11.18%,respectively. Conclusion An.sinensis a main vector of malaria in the malaria-endemic northern part of Anhui Province,had marked resistance to deltamethrin.