石菖蒲化学成分研究

Chemical Constituents of Acorus tatarinowii Schott

为研究石菖蒲根茎部位的化学成分,利用系统溶剂提取法、正相和反相硅胶柱色谱法、半制备型高效液相色谱法进行了分离和纯化,并采用NMR谱学技术进行结构鉴定,最后得到5种化合物,分别鉴定为顺式甲基异丁香酚(化合物Ⅰ),细辛醛(化合物Ⅱ),苯甲酸(化合物Ⅲ),豆甾醇(化合物Ⅳ),菖蒲醇酮(化合物Ⅴ),且化合物Ⅲ为首次从该植物中分离而得.为深入研究石菖蒲提供了理论依据.

The chemical constituents in the rhizome of Acorus tatarinowii Schott were systematically investigated, five compounds were isolated by solvent extraction, silica gel, and reversed-phase silica gel column chromatography and semipreparative high performance liquid chromatography. Their structures were determined by NMR spectroscopy. The five compounds were isolated and identified as cis-methylisoeugenol （ I ）, asarylaldehyde （ II ）, benzoic-acid （ III ）, stigmasterol（ IV ） , ealamenone（ V ）. Compoud III were obtained from the plant for the first time, The study provides a theoretical basis for the further study on Acorus tatarinowii.