1Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and- lumpectomy plas irradiation for the teatment of invasive breast cancer [J]. NEnglJMed, 2002,347(16) :1233-1241.
2Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follotw-up of a randomized study comparing breust cancer-com-serving surgery with radical mastectomy for esrly breast cancer[ J]. N Engl J Med, 2002,347 ( 16 ) : 1227-1232.
1Bedwinek J. Treatment of stage I and Ⅱ adenocarcinoma of the breast by tumor excision and irradiation. Int J Radiat Oncol Biol Phys, 1981,7: 1553-1559.
2Park CC, Mitsumori M, Nixon A, et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol,2000, 18: 1668-1675.
3Smitt MC, Nowels KW, Zdeblick MJ, et al. The importance of the lumpectomy surgical margin status in long-term results of breast conservation. Cancer, 1995,76:259-267.
4Bartelink H, Horiot JC, Poortmans P, et al. Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med,2001,345:1378-1387.
5National Institutes of Health. NIH consensus conference on the treatment of early-stage breast cancer. JAMA,1991,265:391-395.
6Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med,2002,347: 1233-1241.
7Liljegren G, Holmberg L, Bergh J, et al. 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial. J Clin Oncol,1999,17:2326-2333.
8Renton SC, Gazet JC, Ford HT, et al. The importance of resection margin in conservative surgery for breast cancer. Eur J Surg Oncol,1996,22:17-22.
9Clark RM, Whelan T, Levine M, et al. Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst,1996,88:1659-1664.
10Forrest AP, Stewart HJ, Everington D, et al. Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group. Lancet,1996,348:708-713.
4Van Dongcn JA, Voogd AC, Fcntimcn IS, ct al. Long-term results of a randomized trial comparing breast-conserving therapy with mas- tectomy: European Organization for Research and Treatment of Cancer [J]. J Natl Cancer Inst, 2010, 93(14): 1143-1144.
5Gonzalcz AM, Morales VF, Hortobagyi GN. Ovcricw of resistance to systemic therapy in patients with breast cancer [J]. Adv Exp Mcd Biol, 2010, 608(1): 1-22.
7Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow- up of a randomized study comparing breast cancer-conserving surgery with radical mastectomy for early breast cancer[J]. N Eng J Med, 2002, 347(16): 1227-1232.