复方祛风缓释片中青风藤的提取纯化工艺研究

The extraction and purification process of Qing Feng Teng in the Compound Qufeng sustained-release tablets

目的优选复方祛风缓释片中青风藤的提取纯化工艺。方法以青藤碱作为指标,采用正交试验和单因素相结合的方法优选青风藤提取纯化工艺。结果青藤碱最佳提取工艺为:70%的乙醇6倍量提取2次,每次2 h;纯化工艺为:加1%HCl调pH值为2,氯仿萃取5次。结论该提取纯化工艺科学、合理。

Objective Optimization of the extraction and purification process of Qing Feng Teng in the Compound Qufeng sustained - release tablets. Method With sinomenine as an indicator,orthogonal test and single factors combined to optimize of extraction and purifica- tion process of Qing Feng Teng. Result The best extraction of Sinomenine is ： 70% ethanol 6 times capacity of Caulis Sinomenii, extracted 2 times, 2 hours per time; the purification technology are ： using dilute HCl to adjust PH to 2, then adding chloroform to extract 5 times. Conclusion The extraction and purification is scientific and rational.