细胞因子与腹膜血管新生

Cytokines and Peritoneal Angiogenesis

长期腹膜透析会引起腹膜血管生成,对腹膜功能有重大的影响。细胞因子的表达变化在血管新生中起重要的调节作用。目前引起腹膜血管新生的机制还不十分清楚,一般认为正常情况下血管生成的诱导剂与抑制剂处于平衡状态,一旦此平衡被打破,诱导剂多于抑制剂,就会激活内皮细胞长出新血管,反之,则抑制内皮细胞生长使血管退化。现就近年来细胞因子与腹膜血管新生的研究进展予以综述。

Chronic peritoneal dialysis can cause peritoneal angiogenesis, with a great impact on peritoneal function. At present the peritoneum angiogenesis mechanism is not clear. The changes of cytokines expression play an important role in the regulation of angiogenesis. Here is to review the recent progresses in the research of cytokines roles in peritoneal angiogenesis.