蛙皮活性抗菌肽最新研究进展

Progress in Research of Active Antimicrobial Peptides from the Skins of Frog

蛙皮抗菌肽是生物界中广泛存在的一类生物活性肽,是蛙类生物机体先天性免疫系统中的重要成分。目前,从青蛙皮肤中获得了越来越多结构新颖、作用独特的活性抗菌肽,有望成为感染类以及糖尿病等疾病新的药物资源。此文通过对国内外相关文献进行检索,综合了国内外近年来的研究,对近年来蛙皮抗菌肽的活性研究概况进行综述。

Antimicrobial peptide from the skins of frog is a kind of bioactive peptide existed extensively in nature, and is one key component of the host-resistance apparatus so-called innate immunity. At present, a series of antimicrobial peptide with novel structures and unique function were isolated from frog resources, which were potential resources for anti-infective and diabetes therapeutic drug. By literature retrieval and induction, the progress in research of antimicrobial peptide from the skins of frog was reviewed in this paper.