河南省2006-2010年艾滋病单方阳性配偶阳转状况分析

Analysis on sero-conversion status of HIV-discordant spouse from 2006-2010 in Henan province

目的了解2006-2010年河南省艾滋病单方阳性配偶管理状况及阳转情况。方法通过“河南省艾滋病感染家庭随访管理分析系统”收集2006-2010年全省艾滋病单方感染家庭相关资料，对单方阳性配偶管理状况及阳转情况进行分析。结果河南省艾滋病单方阳性配偶2006～2009年HIV抗体的阳转率分别为1．94／100人年、1．79／100人年、0．59／100人年和0．41／100人年，并呈现逐年下降趋势。同年阳转病例中，除2007年男性明显多于女性外，其他年度男女性别阳转率差异无统计学意义。阳转时间〉2．5年病例所占比例有所增加。绝大多数单方阳性夫妻间的性生活频率在1—4次／月，并能坚持使用安全套。结论河南省单方阳性配偶人群规模稳定，性别比例基本持平；单方阳性配偶随访检测率逐年提高，阳转时间延长，绝大多数夫妻能坚持使用安全套，艾滋病家庭内传播的阳转率得到有效降低。

Objective To study the management status of HIV-discordant family in Henan province from 2006 to 2010. Methods Data on AIDS infected family from ＂AIDS Infected Family Follow-up Management and Analysis System＂ was collected and analized to uderstand the management status of HIV-discordant situation. Results The sero-conversion rates of HIV-discordant spouse were 1.94/100 person-years in 2006, 1.79/100 person-years in 2007, 0.59/100 person- years in 2008 and 0.41/100 person-years in 2009, showing the yearly decrease. Regarding the number of sero-conversion in the same year, male was significantly higher than female in 2007, but not in the other years. The ratio on the course of sero-conversion which was 〉2.5 years was increasing. Frequency of most HIV-discordant couples＇ sexual activities was 1-4 times/month with consistent use of condoms. Conclusion The population of HIV-discordant spouse in Henan province was stable. Regarding management of those HIV-discordant spouse, the acceptance on the rate of test rate was increasing. The course of sero-conversion was also increasing, with most HIV-discordant couples insist on condom use while the sero-conversion rate of HIV-discordant spouse appeared to be low.