ALI/ARDS脏腑证候分布及肺肠相关特征的初步调查

Ditribution of Zang-Fu syndromes and preliminary investigation on characteristcs of "the lung and the large intestine being exterior-interiorly ralted" in ALI/ARDS

[目的]初步明确急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)脏腑证候分布及肺肠相关特征,进一步丰富"肺与大肠相表里"的理论内涵,为制定有效的临床救治方案提供理论依据。[方法]采用临床流行病学横断面调查的方法,收集了86例ALI/ARDS患者临床症状,观察分析其脏腑证候分布情况及肺、肠证候相关性。计数资料采用绝对数进行统计描述,采用二分类Logistic回归分析进行探讨。[结果]ARDS证候表现涉及肺、心、肾及大肠,表现出了多脏腑累及的证候特征;脏腑证候中肺、肠证候具有明显相关性,具体表现为痰热壅肺与肠燥津亏显著相关。[结论]阐明ARDS脏腑证候分布及其相关性特征,可以深化对"肺与大肠相表里"理论的认识,为临床治疗提供理论依据。

[Objective] To preliminarily investigate the distribution of Zang-Fu syndroms and characteristrics of ＂the lung and the large intestine being exterior-exteriorly related＂ in acute lung injury/acute respiratory distress syndrome （ALI/ARDS） and further enrich the theoretical connotation of this therory for providing the theoretic basis for clinically treating and preventing scheme. [Methods] Using clinical epidemiology cross-sectional survey method and collecting the clinical symptoms of 86 patients with ALI/ARDS, the condition in distribution of viscera syndromes and the relevance of lung and large intestine were observed and analyzed. Adopting the absolute number to describe count data, binary variable logistic regression was used to analyze these binary classification variables. [Results] ARDS syndromes performance involved lung, heart, kidney and large intestine, showing a involving characteristics of many viscera syndromes. In viscera syndromes, lung and intestine syndromes had obvious correlation, and the specific performance was the significant correlation between the phlegm-heat clogging the lung and insufficiency of the large intestine fluid. [Conclusion] Exploring lung and large intestine syndrome distribution and the correlation feature can be used to understand deeply the theory of ＂the lung and the large intestine being exterior-interiorly related＂ and provide the theoretic basis for clinical treatment.