摘要
建立和研究了周期药物疗效和潜伏细胞作用的病毒动力学模型,证明了当时,无病平衡点全局渐近稳定,当时,疾病一致持久,且系统存在正的周期解。并用Matlab软件对所得的结果进行了仿真验证。
A virus dynamics model with periodic drug efficacy and exposed cells response was discussed. It was proved that, if, the disease--free equilibrium was global asymptotically stable, if , the disease was uniform persistent. Numerical simulations which support the theoretical analysis were also givetl by using Matlab.
出处
《常州大学学报(自然科学版)》
CAS
2011年第4期75-78,共4页
Journal of Changzhou University:Natural Science Edition
基金
常州大学基础学科基金资助(JS201005)
关键词
周期药物疗效
一致持久
基本再生数
病毒动力学模型
periodic drug efficacy
uniform persistence
the basic reproduction number
virus infection model