丁苯酞软胶囊治疗急性脑梗死疗效观察

Effect observation on Butylphthalide in treatment of acute cerebral infarction

目的观察丁苯酞软胶囊治疗急性脑梗死的临床疗效及安全性。方法 120例急性脑梗死患者随机分为治疗组和对照组各60例,对照组给予阿司匹林、疏血通等常规治疗,治疗组在对照组的基础上加用丁苯酞软胶囊,分别在第1d、第14d、第28d对两组患者进行NIHSS评分及不良反应观察。结果两组患者14d、28d的NIH-SS评分均较治疗前明显好转,治疗组优于对照组,差异有显著性(P<0.01),而两组的肝功、肾功、血凝常规比较差异无显著性。结论丁苯酞软胶囊治疗急性脑梗死能有效改善神经功能缺损症状且相对安全。

Objective To observe the clinical effects and safety of drug butylphthalide in the treatmant of acute cerebral infarction.Methods One hundred and twenty patients with acute cerebral infarction were divided into two groups at random.Sixty patients in control group were treated with Aspirin,Shuxuetong,and so on,while treatment group were given butylphthalide and individually the former basic treatment,with a course of 28d for each group.All selected patients were undertaken the NIHSS before and after the treatment.Results After treatment,there was a significant difference in the NIHSS between treatment group and control group at 14d and 28d（P〈0.05）.Conclusions Butylphthalide is effective and safe for acute cerebral infarction.