佛山地区甲真菌病感染情况的调查研究

Investigation of pathogenic fungi of onychomycosis in Foshan

目的研究佛山地区甲真菌病感染情况、菌种类型以及所占比例。方法收集2010年8月至2011年8月到本院皮肤科就诊的657例甲病患者标本,同时对标本进行真菌学检查、培养及鉴定。结果 657例甲病患者中真菌培养阴性426例,阳性231例,阳性率35.2%。阳性菌中酵母菌124例占53.7%,其中白色念珠菌、近平滑念珠菌、热带念珠菌分别占25.1%、13.9%、8.7%;皮肤癣菌占41.1%,其中红色毛癣菌、须癣毛癣菌所占比例分别为23.8%、13.4%;霉菌所占比例为5.2%,以曲霉菌和青霉菌为主,分别占3.5%和1.3%,不排除污染。结论佛山地区甲真菌病主要致病菌为酵母菌、其次为皮肤癣菌和霉菌,菌种以白色念珠菌、红色毛癣菌、近平滑念珠菌、须癣毛癣菌和热带念珠菌最多见。

Objective To study the infection, strains type and percentage of the onychomycosis in Foshan. Methods To collect the samples of 657 onychomycosis patients from August 2010 to August 2011, then analyzed the samples by means of mycologic examination, fungal culture and identification. Results Of all the 657 cases of onychomycosis, the negatives bacteria were 426 and the positive bacteria were 231 and the positive rate was 35.2%. Among the positive bacteria, the rates of yeast, dermatophytes and mould were 53.7%, 41.1% and 5.2%. Conclusion The research indicated that yeasts, dermatophytes and mould were causative pathogens of onychomycosis in Foshan. Candida albicans, trichophyton rubrum, candida parapsilosis, trichophyton mentagrophytes and candida tropicalis were most frequently isolated.