微波消解-电感耦合等离子体质谱法测定尿中铅的分析质量控制

Analytical Quality Control of Determination of Lead in Urine by Microwave Digestion and Inductively Coupled Plasma Mass Spectrometry

[目的]通过对微波消解的电感耦合等离子体质谱法测定尿中铅,实施分析质量控制和进行分析误差预测,了解实验室铅检测能力和质量控制能力,提高实验室检测结果的准确性和可比性。[方法]按水质分析评价微量元素精密度和准确度中的实验室内部质量控制工作程序进行。[结果]各种溶液测定的总标准差(St)均小于其浓度的5%,总平均回收率可信限(R/d=1.03)在允许范围内,质控考核结果为满意。[结论]用微波消解的电感耦合等离子体质谱法测定尿中铅,实验室分析误差可控制在容许值内。

[ Objective ] To implement analytical quality control and predict analysis error of lead determination in urine by microwave digestion and inductively coupled plasma mass spectrometry （ICP-MS）, so as to investigate the laboratory lead testing and quality control capability, and to enhance the accuracy and comparability of laboratory testing results. I Methods ] According to the water laboratory analytical quality control （AQC/WATER） procedure for precision and accuracy of trace elements, the analysis was processed. Results ] Total standard deviation of every solution was less than 5% （W） of the concentration, and confidence limit of total average rate of recovery （R/d=l.03） was in allowable range. The testing result of the blind samples was satisfactory. E Conclusion ] The laboratory analysis error of lead determination in urine by microwave digestion and ICP-MS can be controlled in the permitted range.