血清胱抑素-C水平在骨性关节炎诊断中价值

Value of serum cystatin-C level to the diagnosis of osteoarthritis

目的探讨血清胱抑素-C水平早期诊断骨性关节炎的价值。方法 196例骨性关节炎患者(观察组),其中早期129例,中期67例,60名健康体检者(对照组),检测2组患者血清胱抑素-C水平,并进行比较。结果早期、中期骨性关节炎患者血清胱抑素-C水平分别为(1.27±0.53)mg/L和(1.43±0.61)mg/L,均高于对照组(0.92±0.38)mg/L,(P<0.01)。结论血清胱抑素-C水平对早期诊断骨性关节炎有一定参考价值。

Objective To study the correlation between serum cystatin-C level and osteoarthritis.Methods A total of 196 patients with osteoarthritis（the observation group） including 129 early osteoarthritis patients and 67 medium-term osteoarthritis patients,and another 60 healthy subjects（control group） were detected and analyzed the serum cystatin-C level.Results The serum cystatin-C level was（1.27±0.53） mg/L in early osteoarthritis patients,and（1.43±0.61） mg/L in medium-term osteoarthritis patients,which was significantly higher than that in control group（0.92±0.38） mg/L（P0.01）.Conclusion The serum cystatin-C level is of referential value to the early diagnosis of osteoarthritis.