期刊文献+

氟比洛芬酯联合舒芬太尼对心脏瓣膜置换术后镇痛作用 被引量:4

原文传递
导出
摘要 目的比较氟比洛芬酯联合舒芬太尼与舒芬太尼用于心脏瓣膜置换术后静脉镇痛的效果与不良反应。方法行心脏瓣膜替换术患者60例,随机分为A,B 2组各30例。2组均采用静脉吸入复合全身麻醉。A组术后镇痛给予舒芬太尼3μg/kg+生理盐水稀释至100mL;B组给予氟比洛芬酯200mg+舒芬太尼1.5μg/kg+生理盐水稀释至100mL。观察并记录术后2,8,12,24,48h的VAS评分,平均动脉压、心率、呼吸频率和脉搏血氧饱和度,并比较2组恶心、呕吐、头晕等不良反应发生率。结果 2组术后各时间点平均动脉压、心率、呼吸频率和脉搏血氧饱和度比较差异无统计学意义(P>0.05);2组术后各时间点VAS评分比较差异无统计学意义(P>0.05);B组恶心、呕吐、头晕发生率低于A组(P<0.05)。结论氟比洛芬酯联合舒芬太尼用于心脏瓣膜置换术后静脉镇痛安全有效,可减少舒芬太尼的用量,降低不良反应发生率。
出处 《中华实用诊断与治疗杂志》 2012年第1期69-71,共3页 Journal of Chinese Practical Diagnosis and Therapy
  • 相关文献

参考文献5

  • 1Vaughan R S. Pain relief after thoracotomy[J]. Br J Anaesth, 2001,87(5):681-683.
  • 2Della Rocca G, Coccia C, Pompei L, et al. Post thoracotomy analgesia: epidural vs intravenous morphine continuous infusion [J]. Minerva Anestcsiol,2002,68(9):681-693.
  • 3Schulze S, Thorup J. Pulmonary function, pain, and fatigue after laparoscopic cholecystectomy[J]. Eur J Surg,1993,159(6- 7):361-364.
  • 4高珲.开胸术后应用氟比洛芬酯复合舒芬太尼镇痛效果观察[J].中华实用诊断与治疗杂志,2010,24(12):1220-1221. 被引量:4
  • 5RaoA S, Cardosa M, Inbasegaran K. Morphine sparing effect of ketoprofen after abdominal surgery[J]. Anaesth Intensive Care,2000,28(1):22-26.

二级参考文献4

共引文献3

同被引文献49

  • 1孙晋华,翟俊格,李常新,梁智星.脑血流及微栓子在心脏瓣膜置换术中的监测分析[J].中华医学超声杂志(电子版),2013,10(8):644-646. 被引量:1
  • 2Alexander S, de Vos W M, Castle T C, et al. Growth and shrinkage of pluronic micelles by uptake and release of flurbiprofen: variation of pH[J]. I.angmuir,2012,28(2):6539- 6545.
  • 3Qayyurn A, Najmi M H, Farooqi Z W. Determination of pharmacokinetics of flurbiprofen in Pakistani population using modified HPLC method[J]. J Chromatogr Sci,2011,49(4) :108- 113.
  • 4Alexander S, Cosgrove T, Prescott S W, et al. Flurbiprofen encapsulation using pluronic triblock copolymers[J], Langnmir, 2011,27(13) :8054- 8060.
  • 5Fujimoto Y, Nomura Y, Hirakawa K, et al. Flurbiprofen axetil provides a prophylactic benefit against mesenteric traetion syndrome associated with remifentanil intusion during laparotomy[J]. J Anesth,2012,26(4):490 -495.
  • 6Esme H, Kesli R, Apiliogullari B, et al. Effccts of flurbiprofen on CRP, TNF-α, IL-6, and postoperative pain of thoracotomy [J]. Int J Med Sci,2011,8(3):216- 221.
  • 7Chen Y, Sun J, Huang Z, et al. Design, synthesis and evaluation of tacrine-flurbiprofen nitrate trihybrids as novel anti Alzheirner's disease agents[J]. Bioorg Med Chen,, 2013,21 (9):2462- 2470.
  • 8Duncan K, Uwimpuhwe H, Czibere A, et al. NSAIDs induce apoptosis in non proliferating ovarian cancer cells and inhibit tumor growth in vivo[J]. IUBMB Life,2012,6,1(7):636 -643.
  • 9Aida S, Baba H, Yamakura T, et al. The effectiveness of preemptive analgesia varies according to the type of surgery: a randomized, double-blind study[J]. Anest h Analg, 1999,89 (3): 711-716.
  • 10Zhang Z. Lack of preemptive analgesia by intravenous flurbiprofen in thyroid gland surgery: a randomized, double- blind and placebo-controlled clinical trial [J]. Int J Med Sci, 2011,8(5) :433.

引证文献4

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部