磁敏感加权成像在显示脑梗死血栓中的临床应用价值

Clinical application of susceptibility-weighted imaging in monitoring aterial thrombosis in ischemic stroke

目的：探讨磁敏感加权成像（Susceptibility-weighted imaging，SWI）对脑梗死血管内血栓监测的敏感性及其临床应用价值。方法：对36例（男）9例，女17例，年龄20-83岁，平均65岁）急性脑梗死（临床症状出现24h以内）患者行SWI及随访检查。观察脑梗死血管内的血栓显示及显示程度，得出相应的临床NIHSS评分，并进行相关统计学分析。结果：有27例显示血栓存在，占75％，其中明显显示（血栓长度〉3em）17例，轻度显示（血栓长度〈3cm）10例。大面积脑梗死的血栓显示程度与临床NIHSS评分的改变具有明显相关性（L=0．782，P〈O．01）。结论：SWI能敏感监测急性大面积脑梗死的血栓形成，并根据显示程度预测临床发展趋势，对l临床治疗和预后判断起到一定的指导作用。

Objective： To investigate the sensitivity of susceptibility-weighted imaging（SWI） in displaying atery thrombosis in ischemic stroke, and evaluate the role of SWI in the assessment of arterial thrombosis in ischemic stroke. Methods： Thirty- six patients （19 males, 17 females, age 20-83 years, average 65 years） with acute cerebral infarction （within 24 hours after clinical onset） performed and followed up with SWI. The presence of correlated atery thrombosis within the infarction were observed, the correlation between the extent of the correlate aterial thrombosis. NIHSS was analyzed. Results： The correlated aterial thrombosis was revealed by SWI in 27 out of 36 massive cerebral infarctions, the proportion was 75%. Seventeen were signifcantly showed（the length of aterial thrombosis 〉3era）, 10 were midly showed on the SWI（the length of aterial thrombosis 〈3em）. There was a significant positive correlation between the severe ischemic stroke aterial thrombosis displayed in the SWI and the NIHSS scores （r,=0.782, P〈0.01）. Conclusion： SWI was sensitive in detecting the atery thrombosis in infarction, which can be used to predict the evolution of ischemic stroke, which was helpful in guiding the clinical treatment.