摘要
目的分析老年2型糖尿病患者血尿酸与骨密度是否相关。方法测定121例老年2型糖尿病患者的骨密度及血尿酸浓度,按照性别分为两组,应用SPSS17.0对数据进行相关及回归分析。结果老年2型糖尿病患者血尿酸值与年龄及多部位骨密度值相关,与L2、大转子、股骨干等部位的骨密度值相关性显著(P<0.01)。结论动态监测血尿酸值有利于老年2型糖尿病患者骨密度值减低的预防和治疗。
Objective To analyze the association of serum uric acid with bone mineral density in elderly people with type 2 diabetes mellitus. Methods Dual energy x-ray absorptiometry (DXA) was used to measure BMD of seven skeletal regions of lumbar spine ( L_2-L_4 ) , the left hip department ( femoral neck, Ward's triangle and greater trochanter) and femoral and uricase-peroxidase enzymatic method was used to measure serum uric in 121 elderly people with type 2 diabetes mellitus, in whom were divided into two groups:group I (the old man)and group l] (the postmenopausal women). The data were analyzed by spssl7.0. Results The correlation analysis results showed that: In elderly people with type 2 diabetes mellitus, the serum uric acid level was positively and significantly related to bone mineral density of multi areas. Conclusion It is a good predictor to dynamically monitor the serum levels of UA in the elderly patients with type 2 diabetes mellitus with decrease of BMD, which benefits the prevention and treatment.
出处
《中国骨质疏松杂志》
CAS
CSCD
2011年第12期1052-1055,共4页
Chinese Journal of Osteoporosis
关键词
老年人
2型糖尿病
尿酸
骨密度值
Elderly people
Type 2 diabetes mellitus (T2DM)
Uric acid (UA)
Bone mineral density (BMD)