Wnt信号通路在骨髓间充质干细胞向成骨细胞分化机制的研究进展

Research progress of the mechanisms of Wnt signaling pathway in the differentiation of osteoblasts by bone mesenchymal stem cells

Wnt信号通路是目前骨骼系统相关疾病发病机制和骨代谢研究的新热点,笔者就其对骨髓间充质干细胞向成骨细胞分化的机制及研究现状作详细阐述,旨在为相关研究提供一定的理论依据及参考。

Wnt signaling pathway is a new and hot topic in the research of pathogenesis of skeletal system relateddiseases and bone metabolism. The authors preliminarily summarize the main proportion of Wnt signaling pathway and the classic Wnt/bcatenin signaling pathway, and clearly elaborate the differentiation mechanism of osteoblasts by bone marrow mesenchymal stem cells and the current research status, aiming to provide certain theoretical basis and reference for the related research.