1676例儿童骨髓细胞学诊断结果分析

Analysis of 1676 cases of bone marrow cell cytology examination from children with blood disorders

目的:探讨儿童骨髓细胞形态学特征与临床初步诊断的关系。方法:将2007至2011年我院血液科送检的1 676例儿童骨髓穿刺合格标本,进行细胞形态学检查和(或)细胞特殊免疫细胞化学染色,结合临床资料作出实验室骨髓细胞学诊断。结果:骨髓细胞学诊断结果符合率最高的疾病分别是:原发性血小板减少性紫癜(ITP)占92.3%;缺铁性贫血(IDA)占88.9%;白血病(AL)占85.1%;其中以急性淋巴细胞白血病为多见,占66.4%。结论:骨髓细胞形态学检查对儿童大部分血液病有确诊价值,对某些原因不明的疾病有重要鉴别诊断意义。

Objective： To explore the relationship between children＇s bone marrow cell morphology and initial clinical diagnosis. Methods： 1676 cases of bone marrow specimens were stained by Wright-Giemsa and special histochemical staining from 2007 to 2011.Bone marrow cell cytology diagnoses were given according to the staining results combined with clinical data. Results： Among the bone marrow cell morphology diagnoses the top three diseases were idiopathic thrombocytopenic purpura（ITP）,iron deficiency anemia（IDA） and leukemia with coincident rates of 92.3%,88.9%,85.1% separately.The disease with the highest incidence rate of 66.4% was acute lymphocytic leukemia. Conclusion： Bone marrow cell cytology examination were valuable to the definite diagnoses of most children＇s haematological diseases,and were also meaningful to the differential diagnoses of some obscure diseases.