期刊文献+

浆细胞样树突状细胞在炎症性皮肤病中的作用

The role of plasmacytoid dendritic cell in inflammation skin diseases
下载PDF
导出
摘要 浆细胞样树突状细胞(plasmacytoid dendritic cell,pDC)是最近发现的树突状细胞的一个亚类,有类浆细胞形态,作为CD123+被识别[1],也被称为天然的I型干扰素产生细胞,是最有潜力的I型IFN(IFN-a/β)产生细胞,在对病毒等微生物的反应中,其分泌IFN-a/β的能力是其他细胞的1 000倍[2]。
作者 陈静
出处 《河南医学研究》 CAS 2011年第4期484-487,共4页 Henan Medical Research
  • 相关文献

参考文献27

  • 1Olweus J.Dendritic cell ontogeny:a human dendritic cell lineage ofmyeloid origin[J].Proc Natl Acad Sci USA,1997,94(23):12551-12556.
  • 2Liu Y J.IPC:professional type 1 interferon-producing cells and plas-macytoid dendritic cell precursors[J].Annu Rev Immunol,2005,23:275-306.
  • 3Shigematsu H.Plasmacytoid dendritic cells activate lymphoid-specificgenetic programs irrespective of their cellular origin[J].Immunity,2004,21(1):43-53.
  • 4Weissmann C,Weber H.The interferon genes[J].Prog Nucleic AcidRes Mol Biol,1986,33:251-300.
  • 5Biron C A.Interferons alpha and beta as immune regulators-a new look[J].Immunity,2001,14(6):661-664.
  • 6Le Bon A,Tough D F.Links between innate and adaptive immunityvia type I interferon[J].Curr Opin Immunol,2002,14(4):432-436.
  • 7Le Bon A.Type i interferons potently enhance humoral immunity andcan promote isotype switching by stimulating dendritic cells in vivo[J].Immunity,2001,14(4):461-470.
  • 8Le Bon A.Cross-priming of CD8+T cells stimulated by virus-inducedtype I interferon[J].Nat Immunol,2003,4(10):1009-1015.
  • 9Ahonen C L.Combined TLR and CD40 triggering induces potentCD8+T cell expansion with variable dependence on type I IFN[J].JExp Med,2004,199(6):775-84.
  • 10Takaoka A.Integration of interferon-alpha/beta signalling to p53 re-sponses in tumour suppression and antiviral defence[J].Nature,2003,424(6948):516-523.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部