日本红叶小檗红色素的抑菌性研究

Study on the Antibacterial Activity of the Red Pigment from Berberis thumbergii

研究日本红叶小檗红色素在不同条件下对金黄色葡萄球菌、大肠杆菌、枯草芽孢杆菌的抑菌效果。结果表明:日本红叶小檗红色素对金黄色葡萄球菌、大肠杆菌、枯草芽孢杆菌均有抑制作用,但该色素对金黄色葡萄球菌抑菌性最强,而对枯草芽孢杆菌和大肠杆菌的抑菌性次之,且色素浓度越大抑菌性越强。Ca2+、Fe2+可使日本红叶小檗红色素的抑菌性增强,其中Fe2+的促进作用最大,而Na+、K+可使该色素的抑菌性有所减弱;分别加入葡萄糖、麦芽糖、蔗糖不会使日本红叶小檗红色素的抑菌性产生差异,但糖类可使该色素对大肠杆菌的抑菌性有所加强,对金黄色葡萄球菌的抑菌性明显减弱,对枯草芽孢杆菌的抑菌性没有影响。

Analyzed the bacteriostasis of the red pigment from Berberis thundergii in different conditions. Results showed that the pigment all had bacteriostasis on Staphyloccus aureus, Bacillus subtilis, Escherichia coll. But the pigment had greatest bacteriostasis on Staphyloccus aureus in three bacterium and was the second on Bacillus srtbtilis and Escherichia coll. And the greater bacteriostasis was the higher pigment concentration increases. Caz＋ ,Fez＋ ions had the bacteriostasis of the pigment to increase and affect of Fez＋ ions was greater in two ions, while Na＋ ,K＋ ions had the bacteriostasis of the pigment to weaken, bacteriostasis of the pigment will not produce difference due to add cane sugar, glucose, maltose. But sugar had the bacteriostasis of the pigment on Escherichia coli to increase;And had the bacteriostasis of the pigment on Staphyloccus aureus to weaken; on Bacillus snbtilis had not effect.