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放疗致颈动脉粥样硬化的研究进展 被引量：3

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摘要 放疗是治疗头颈部恶性肿瘤的主要方法之一,但大量的临床和基础研究提示放射线可促使血管内皮活化,并在炎性反应和氧化损伤机制的参与下促进颈动脉粥样硬化的发生、发展,从而增加发生脑血管事件的风险。该文就有关头颈部放疗与颈动脉粥样硬化性损伤关系的研究进行综述。
作者 贺涓涓 洪华
机构地区 中山大学附属第一医院神经内科
出处 《中国神经免疫学和神经病学杂志》 CAS 北大核心 2012年第1期65-68,共4页 Chinese Journal of Neuroimmunology and Neurology
基金 国家自然科学基金资助项目(30971028) 广东省自然科学基金资助项目(0602123) 广州市科技计划资助项目(2009ZL-E021)
关键词 放射疗法 颈动脉疾病 动脉粥样硬化
分类号 R543.4 [医药卫生—心血管疾病] R818 [医药卫生—放射医学]
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参考文献35

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同被引文献33

  • 1Li C S,Schminke U,Tan T Y. Extracranial carotid artery dis-ease in nasopharyngeal carcinoma patients with post-irradiation ischemic stroke[J].Clinical Neurology and Neurosurgery,2010,(08):682-686.
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  • 3Gianicolo M E,Gianicolo E A,Tramacere F. Effects of exter-nal irradiation of the neck region on intima media thickness of the common carotid artery[J].Cardiovascular Ultrasound,2010.8.
  • 4Mil iat F,Francois A,Tamarat R. Role of endothelium in ra-diation-induced normal tissue damages[J].Annales de Cardiologie et d'Angéiologie(Paris),2008,(03):139-148.
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  • 6S oucy K G,Lim H K,Attarzadeh D O. Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dys-function in rat aorta[J].Journal of Applied Physiology,2010,(05):1250-1258.
  • 7Hol er V,Buard V,Gaugler M H. Pravastatin limits radia-tion-induced vascular dysfunction in the skin[J].Journal of Investigative Dermatology,2009,(05):1280-1291.
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  • 9Scott AS, Parr LA, Johnstone PA. Risk of cerebrovascular events after neck and supraclavicular radiotherapy: A systematic review [J]. Radiother Oncol, 2009, 90(2): 163-165.
  • 10Palombo C, Kozakova M, Guraschi N, et al. Radiofrequency- based carotid wall tracking: A comparison between two different systems[J]. J Hypertens, 2012, 30(8): 1614-1619.

引证文献3

二级引证文献4

中国神经免疫学和神经病学杂志
2012年 第1期

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