峨参提取物对肺癌细胞A549和H460增殖的抑制作用初步观察

Tentative Study of Anthriscus Extracts Repressing the Proliferation of Lung Cancer Cell A549 and H460

目的:观察峨参石油醚、氯仿、乙酸乙酯和正丁醇部位提取物对肺癌细胞A549和H460增殖的抑制作用。方法:应用MTT比色法检测不同部位、不同浓度峨参提取物对肺癌细胞A549和H460增殖的抑制作用。结果:10～1000μg/mL的4个部位峨参提取物对体外培养的人肺癌细胞A549和H460的增殖具有抑制作用,其中石油醚部位、氯仿部位和乙酸乙酯部位提取物抑制作用更明显。结论:峨参不同部位提取物对肺癌细胞增殖具有明显的抑制作用。

Objective：To observe the inhibition of petroleum ether,chloroform,ethyl acetate and butanol extracts of Anthriscus sylvestris（L.）Hoffm on the proliferation of lung cancer cell A549 and H460.Methods：To detect the inhibition effects of different parts with different concentrations Anthriscus extracts on the proliferation of lung cancer cell A549 and H460 by MTT assay.Result：4 parts of Anthriscus sylvestris extracts have inhibition effect on the proliferation of lung cancer cell A549 and H460 when concentrations are from 10 to 1000μg/mL,moreover,the extracts of petroleum ether,chloroform and ethyl acetate parts have more obvious evident inhibition.Conclusion：The extracts of different parts of Anthriscus have evident inhibition effect on the proliferation of lung cancer cell.