梅毒螺旋体阳性患者C反应蛋白的变化及意义

The Changes of the Level of CRP in Patients with Positive Treponema Pallidum

目的:观察梅毒抗体阳性患者C反应蛋白水平以探讨其对梅毒螺旋体感染的诊断意义及应用价值。方法:分别检测并比较75例梅毒抗体阳性患者、80例健康正常人C反应蛋白水平,并同时对比分析梅毒患者治疗前后C反应蛋白水平变化情况。结果:观察组梅毒患者治疗前CRP水平显著高于健康正常人组(P<0.001)。Ⅰ期、Ⅱ期、Ⅲ期梅毒患者CRP水平有显著性差异(P<0.01),随患者梅毒分期的增高,CRP水平有所降低。梅毒患者治疗前后CRP水平有统计学差异(P<0.01)。结论:CRP检测在梅毒抗体阳性患者早期诊断、临床分期及治疗转归等方面具有重要应用价值。

Objective： Observing the C-reaction protein（CRP） in patients with positive treponema pallidum to explore the value of CRP in the diagnosis of syphilis.Method：The level of CRP in 75 cases of positive treponema pallidum,80 cases of health was detection,and also after the treatment of syphilis.Result：There was significant difference between the patients of positive treponema pallidum and the health in the level of CRP（P0.001）.There＇s evident difference in clinical stages of Ⅰ,Ⅱ,Ⅲ（P0.001）.Compared with the level of CRP in patients with positive treponema pallidum before treatment,there was obvious difference after treatment（P0.01）.Conclusion： CRP testing to patients with positive treponema pallidum has application value in early diagnosis,the clinical stages,and treatment outcome.