北京市昌平区健康人群风疹和流行性腮腺炎抗体水平监测分析

Monitoring of Rubella and Mumps Antibody Levels Among Healthy Population in Changping District,Beijing

目的了解昌平区健康人群风疹、流行性腮腺炎(简称流腮)抗体水平,为传染病控制工作提供科学依据。方法采集昌平区10个村本市及外省人口血标本共220份,采用酶联免疫吸附试验(ELISA)测定风疹、流腮IgG抗体,同时调查风疹、流腮患病史和免疫史及人口学特征。结果 220名调查对象的风疹抗体阳性率为75.00%,其中本市110人抗体阳性率为74.55%,外省110人抗体阳性率为75.45%。风疹IgG抗体浓度均数为64 IU/ml,其中1～4岁年龄组最高,为124 IU/ml。0～1岁年龄组最低,为3 IU/ml;流行性腮腺炎抗体阳性率为80.45%,其中本市110人抗体阳性率为80.91%,外省110人抗体阳性率为80.00%。流腮IgG抗体浓度均数为436 IU/ml。其中20～24岁年龄组最高,为664IU/ml,0～1岁年龄组最低,为122 IU/ml。结论提高麻风腮疫苗基础免疫接种率,在儿童入学前完成1剂加强免疫,对控制风疹和流行性腮腺炎有重要意义。同时应关注成人尤其是育龄期妇女的免疫接种,以减少先天性风疹综合征的发生。

Objective To investigate the antibody levels of rubella and mumps among the healthy crowd in Changping District, and to provide a scientific basis for infectious disease control work. Methods Totally 220 serum samples were collected from the local and floating population in 10 villages of Changping District. The rubella and mump IgG antibody levels were determined by ELISA. The medical history, immune history and demographic characteristics of rubella and mumps were surveyed. Results The positive rate of rubella antibody in 220 investigated objects was 75.00 %, the antibody positive rate of 110 local investigated objects was 74.55 % and that of 110 non - permanent residents was 75.45 %. The mean IgG antibody concentration of rubella was 64 IU/ml, among them the age group of 1-4 years was the highest （124 IU/ml）, while the age group of 0-1 years was the lowest （3 IU/ml）. The antibody positive rate of mumps in 220 investigated objects was 80.45 %, among them the antibody positive rate of 110 local investigated objects was 80.91% and the antibody positive rate of 110 non - permanent residents was 80.00%. The mean IgG antibody concentration of mumps was 436 IU/ml, among them the age group of 20--24 years was the highest （664 IU/ml） and the age group of 0-- 1 years was the lowest （ 122 IU/ml）. Conclusions Improving the basic vaccination rate and comPleting the booster immunization before children going to school have an important significance in control of rubella and mumps. At the same time, it is necessary to focus on the immunization of adults especially women at childbearing age so as to reduce the occurrence of congenital rubella syndrome.