不同类型的突发性耳聋的临床疗效观察

目的观察并比较大剂量激素和前列地尔联合治疗不同类型的突发性耳聋的临床疗效。方法选择以低频听力下降为主的突发性耳聋42人,病耳45例,全频率都下降的突发性耳聋43人,病耳44例,高频率下降为主的突发性耳聋40人,病耳50例。每组给予的治疗方案相同:10mg地塞米松加入0.9%氯化钠注射液100mL,静脉滴注3天,5mg地塞米松加入0.9%氯化钠注射液100mL静脉滴注2天,联合前列地尔20μg加入0.9%氯化钠注射液100mL中静脉滴注,每日一次,10d为1疗程。结果 3组的治愈率分别为33.3%、13.53%和8%,差异有统计学意义(P<0.05);三种不同类型的突发性耳聋临床疗效比较,H值为16.28,P<0.05,有统计学意义。结论低频听力下降型的突发性耳聋的临床疗效高于其他两型。

Objective Observe and compare the high-dose hormones and alprostadil in the treatment of sudden deafness of different types of clinical efficacy.Methods Choose to mainly low-frequency hearing loss sudden deafness 42 persons,including 45 cases of ear disease,Decline in full-frequency sudden deafness 43 persons,including 44 cases of ear disease,mainly high-frequency drop of sudden deafness 40 persons including 50 cases of ear disease.Each group given the same treatment：10mg dexamethasone in 0.9% sodium chloride injection 100 mL,intravenous infusion of 3 days,5mg Dexamethasone 0.9% sodium chloride injection 100 mL intravenous infusion of 2 days,joint alprostadil 20μg in 0.9% chlorine sodium chloride injection 100 mL in intravenous infusion once a day,10d course of treatment.Results 3 group cure rates were 33.3%,13.53% and 8%;three different types of clinical effects of sudden deafness,H is 16.28,P0.05,statistically significant.Conclusion The clinical curative effect of sudden deafness in Low frequency hearing loss is higher than other types.