高频超声在2型糖尿病与高血压患者对下肢动脉粥样硬化影响的对比研究应用

Comparative Study of High-frequency Color Doppler Ultrasonography on the Impact of Atherosclerosis in Lower Limbs of Patients with Type 2 Diabetes and Hypertension

目的研究糖尿病(DM)与高血压(HP)患者下肢动脉粥样硬化(AS)的发病率,重视DM患者AS的防治,为临床提供理论依据。方法应用高频彩色多普勒超声观察130例DM合并AS患者与100例单纯HP患者对照组下肢动脉。对两组下肢动脉内-中膜厚度、有无粥样硬化斑块的发生、管径狭窄或闭塞及血流动力学改变进行比较。结果 DM组下肢血管管腔的内-中膜厚度、硬化斑块、狭窄、闭塞的发生率明显高于HP组。内-中膜厚度增加及硬化斑块的发生率以动脉分叉bifurcation明显,而管腔狭窄、闭塞以股浅、胫前动脉为重,足背动脉最重。结论 DM患者较单纯HP患者更容易并发和加重下肢AS,高频彩色多普勒超声检查可以为临床诊疗提供可靠的信息。

Objective To invest the incidence of atherosclerosis in lower limbs among patients with Diabetes mellitus and Hypertension, thus provide a theoretical basis for clinical practice. Methods Observe Arteries of lower extremity in 130 patients of Diabetes mellitus with compIications of Atherosclerosis and 100 patients with hypertention. Then compare the thickness of tunica media and tunica intima, the incidence of atherosclerotic plaque, stenosis or emphraxis, and the changes of hemodynamics between the two groups. Results Patients with DM had thicker tunica media and tunica intima, higher incidence of atherosclerotic plaque, stenosis and emphraxis than patients with HE Incresed thickness of tunica media and tunica intima and atherosclerotic plaque occurred more often in artery bifurcation. While stenosis and emphraxis are often more serious in superficial femoral artery, anterior tibial artery and dorsal pedis artery. Conclusion Patients with Diabetes mellitus have a higher risk than those with Hypertension to develop and aggravate Atherosclerosis. Color Doppler ultrasound can provide reliable information for clinical diagnosis and treatment.