期刊文献+

多排螺旋CT双动脉期增强扫描对比剂浓度对肝癌检出率的影响 被引量:12

Detection of Hepatocellular Carcinoma with Multi-detector Row CT by Using Double-arterial Phase Enhanced Scanning:Effect of Iodine Concentration of Contrast Material
下载PDF
导出
摘要 目的:通过多排螺旋CT双动脉期及门脉期增强扫描,以评估对比剂浓度对肝癌检出率的影响。方法:95例肝癌患者随机分为两组行多排螺旋CT肝脏平扫及双动脉期、门脉期增强扫描,其中一组(48例)注射碘帕醇370mgI/ml(1.5 ml/kg),另外一组(47例)注射碘帕醇300mgI/ml(1.85ml/kg),均于30s注射完毕。扫描后图像由放射科医生阅片并与病理结果进行对比,统计分析两组患者>2cm及≤2cm的肝癌病灶的诊断敏感性。结果:95例患者中共证实有259个肝癌病灶,其中87个≤2cm,172个>2cm。对于≤2cm的病灶及所有病灶动脉早期及晚期370mgI/ml组诊断敏感性高于300mgI/ml组,差别有统计学意义;在门脉期两组患者的诊断敏感性无显著性差异。结论:高浓密度对比剂在动脉早期、晚期可提高肝癌的检出率,特别是对于较小的肝癌病灶(≤2cm)。 Purpose: To evaluate the effect of iodine concentration of contrast material on detection of hepatocellular carcinoma (HCC) with multi detector row CT by using double arterial phase and portal venous phase enhanced scanning. Methods: Ninety five patients with HCC were examined by hepatic plain CT and contrast enhanced CT including early arterial phase(EAP), late arterial phase (LAP) and hepatic parenchymal phase (HPP) scanning prospectively. Patients were randomized into two groups to receive Iopamidol 370 mgI/ml (48 patients, 1.5 ml/kg body weight) and 300 mg I/ml (47 patients, 1.85 ml/ kg body weight) respectively with a fixed injection duration of 30 seconds. The images were inter preted by radiologists and the CT results were compared with the pathological results. The detection sensitivity for tumors of two size categories (≤ 2 cm or 〉 2 cm) and iodine concentration groups were calculated and analyzed.Results: A total of 259 lesions were detected with 87 less than 2 cm in size and 172 larger than 2cm in size. For EAP and LAP, the sensitivity of Iopamidol 370 mg I/ ml group was sig nificantly higher than Iopamidol 300 mg I/ ml group for tumors ≤2cm in size and all tumors. For HPP, there was no significant difference between groups. Conclusion: High iodine concentration contrast ma terial could imorove the detection of HCC during EAP and LAP, esoecially for tumor ≤ 2cm in size.
出处 《中国医学计算机成像杂志》 CSCD 北大核心 2011年第5期394-398,共5页 Chinese Computed Medical Imaging
关键词 多排螺旋CT 对比剂 肝癌 Multi detector row CT Contrast material Hepatocellular carcinoma
  • 相关文献

参考文献14

  • 1Murakami T,Kim T,Hori M,et al.Double arterial phase multidetector row helical CT for detection of hypervascular hepatocellular carcinoma.Radiology,2003,229:931-932.
  • 2Ichikawa T,Kitamura T,Nakajima H,et al.Hypervascular hepatocellular carcinoma:can double arterial phase imaging with multidetector CT improve tumor depiction in the cirrhotic liver.Am J Roentogenol,2002,179:751-758.
  • 3Pozzi Mucelli RM,Como G,Del Frate C,et al.Multidetector CT with double arterial phase and high-iodine-concentration contrast agent in the detection of hepatocellular carcinoma.Radiol Med,2006,111:181-191.
  • 4Murakami T,Kim T,Takamura M,et al.Hypervascular hepatocellular carcinoma:detection with double arterial phase multidetector row helical CT.Radiology,2001,218:763-767.
  • 5Schima W,Hammerstingl R,Catalano C,et al.Quadruplephase MDCT of the liver in patients with suspected hepatocellular carcinoma:effect of contrast material flow rate.AJR,2006,186:1571-1579.
  • 6Iannaccone R,Laghi A,Catalano C,et al.Hepatocellular carcinoma:role of unenhanced and delayed phase multi-detector row helical CT in patients with cirrhosis.Radiology,2005,234:460-467.
  • 7Yanaga Y,Awai K,Nakayama Y,et al.Pancreas:patient body weight tailored contrast material injection protocol versus fixed dose protocol at dynamic CT.Radiology,2007,245:475-482.Epub 2007 Sep 21.
  • 8Tublin ME,Tessler FN,Cheng SL,et al.Effect of injection rate of contrast medium on pancreatic and hepatic helical CT.Radiology,1999,210:97-101.
  • 9Yagyu Y,Awai K,Inoue M,et al.MDCT of hypervascular hepatocellular carcinomas:a prospective study using contrast materials with different iodine concentrations.AJR,2005,184:1535-1540.
  • 10Awai K,Takada K,Onishi H,et al.Aortic and hepatic enhancement and tumor-to-liver contrast:analysis of the effect of different concentrations of contrast material at multi-detector row helical CT.Radiology,2002,224:757-763.

同被引文献123

引证文献12

二级引证文献77

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部