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HAG方案治疗中高危骨髓增生异常综合征及低增生髓系白血病 被引量:2

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摘要 目的:观察高三尖杉酯碱(HHT)、阿糖胞苷(Ara-C)和粒细胞集落刺激因子(G-CSF)联合方案(HAG方案)治疗中高危骨髓增生异常综合征(MDS)以及低增生髓系白血病(AML)的临床疗效。方法:应用HAG方案治疗MDS 6例和AML 12例,1个疗程诱导治疗失败后继用1个疗程治疗,观察治疗的效果及不良反应。结果:6例MDS完全缓解(CR)4例,部分缓解(PR)1例,总有效率83.3%;12例AML患者CR 6例,PR 2例,总有效率66.6%;大部分患者出现了可以耐受的不良反应,主要表现为骨髓抑制。结论:HAG治疗中、高危MDS以及低增生AML近期疗效显著,不良反应轻。
出处 《贵阳医学院学报》 CAS 2011年第6期640-641,643,共3页 Journal of Guiyang Medical College
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