上海市第一批一线抗反转录病毒治疗失败病例更换二线药物一年后情况分析
摘要
上海市公共卫生临床中心自2005年10月起根据国家相关政策，对上海市的患者以及长期居住在上海的外地患者进行免费抗反转录病毒治疗（ART）。国家免费治疗手册中建议成人的一线抗病毒治疗方案为两种核苷类药物（NRTIs）和一种非核苷类药物（NNRTIs），即司他夫定或齐多夫定＋拉米夫定（3TC）＋奈韦拉平或依非韦伦，二线药物有替诺福韦（TDF）、洛匹那韦/利托那韦（LPV／r）。随着治疗时间的延长，部分患者已出现一线药物治疗失败。
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2011年第12期744-748,共5页
Chinese Journal of Infectious Diseases
基金
国家“十一五”传染病重大专项艾滋病合并结核分枝杆菌感染人群治疗策略研究项目（2008ZX1OOO1-008）
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