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人类免疫缺陷病毒-1型反式转录激活因子诱导机体免疫应答的研究进展

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摘要 反式转录激活因子(transactivaloroftronscription.Tat)是HIVl在感染早期产生的一种重要调节蛋白,它可与HIV-1RNA基因组的反式激活效应元件(transactivatingresponsiveregion,TAR)结合,促进HIV-1的转录及复制,在HIV-1感染及致病中发挥重要作用。
出处 《中华传染病杂志》 CAS CSCD 北大核心 2011年第12期762-764,共3页 Chinese Journal of Infectious Diseases
基金 国家自然科学基金资助项目(30972799、30872246) 上海市基础研究重点项目(08JCl405200)
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