河北省沿海水源性高碘地区甲状腺癌流行病学调查

Epidemiological Study of Thyroid Cancer in Coastal Water Born Periodic Region in Hebei

目的:对河北省沿海水源性高碘地区2005年至2009年间甲状腺癌发病率和死亡率进行统计分析,了解其分布特征及变化趋势,为预防及干预甲状腺癌的发病提供基础。方法:采用描述流行病学的方法,对河北省沿海水源性高碘地区近5年甲状腺癌的发病率、标化发病率、死亡率、标化死亡率并进行分析。结果:2005年至2009年间河北省沿海水源性高碘地区平均发病率为3.000/10万,标化发病率为1.443/10万,男女粗发病率性别比为1:3.070,平均死亡率为0.390/10万,标化死亡率为0.190/10万研究显示,5年来男女甲状腺癌发病率呈逐年上升趋势,尤其女性35～50岁年龄组甲状腺癌为高发。结论:甲状腺癌发病率增长较快,尤其是对年轻女性影响更为明显;死亡率无明显变化。需积极寻求相关危险因素,采取相应预防、干预措施,降低发病率。

Objective： To investigate the incidence and mortality of thyroid cancer in Hebei Province, which is an area with high iodine concentration in drinking water, from the year 2005 to 2009, in order to understand the distributional characteristics and change trends and provide a basis for the prevention and intervention measures. Methods： Descriptive epidemiological methods were used to analyze the incidence, standardized incidence, mortality, and standardized mortality of thyroid cancer in Hebei. Results： In the years 2005 to 2009, the average incidence rate of thyroid cancer in Hebei was 3.000/100,000. The standardized rate was 1.443/100,000, whereas the male to female ratio of crude incidence was 1：3.07, with an average mortality rate of 0.390/100,000, and a standardized mortality 0.190/100,000. Studies showed that the 5-year incidence of thyroid cancer in men and women displayed an increasing trend over the years, and a high incidence of thyroid cancer was seen particularly in women belonging to the age group of 35 years to 50 years. Conclusion： The incidence of thyroid cancer has increased rapidly, with young women in particular being the more affected population group. No significant changes were seen in mortality. More studies should be done to explore relevant risk factors, and corresponding prevention and intervention measures should be taken to reduce the incidence.