摘要
目的:研究银线草(Chloranthus japonicus)全株的化学成分;方法:利用各种色谱方法进行分离;通过各种光谱方法鉴定化合物结构;结果:从银线草分离得到1个新的倍半萜chlojaponilactoneA(1)和5个已知倍半萜:白术内酯III(2),neolitacumoneB(3),10α-hydroxy-1-oxoeremophila-7(11),8(9)-diene-8,12-olide(4),银线草内酯C(5)和银线草内酯H(6);结论:chlojaponilactoneA(1)为新的桉烷型倍半萜内酯,化合物3和4首次从该植物中分离得到。
AIM: To study the chemical constituents of the whole plant of Chloranthusjaponicus. METHODS: Compounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods. RESULTS: Six sesquiterpenoids were obtained and their structures were identified as chlojaponilactone A (1), atractylenolide III (2), neolitacumone B (3), 10a-hydroxy-l-oxoeremophila-7(11), 8(9)-diene-8, 12-olide (4), shizukanolide C (5), and shizukanolide H (6). CONCLUSION: Compound 1 is a new eudesmane-type sesquiterpenoid lactone, and compounds 3 and 4 have been isolated from this species for the first time.
作者
房平磊
刘海洋
钟惠明
FANG Ping-Lei;LIU Hai-Yang;ZHONG Hui-Min(State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences Kunming 650204,China;College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)
出处
《中国天然药物》
SCIE
CAS
CSCD
2012年第1期24-27,共4页
基金
supported by the National Natural Science Funding of China(No.81072543)
the Key Project of Knowledge Innovation Project of CAS(No.KSCX2-EW-Q-10)~~
关键词
银线草
化学成分
倍半萜
桉烷型
Chloranthusjaponicus
Chemical constituents
Sesquiterpenoid
Eudesmane