妇科手术患者子宫内膜异位症发病因素分析

Analysis on the risk factors of endometriosis among the patients undergoing gynecological operation

目的:探讨子宫内膜异位症在妇科手术患者中发病的相关危险因素。方法:选择99例行妇科手术证实为非内异症的良性疾病患者为对照组,选择95例子宫内膜异位症患者为病例组,对两组进行回顾性病例对照分析,对17个相关因素进行单因素、多因素非条件Logistic回归分析。结果:孕次、产次、人流次数、体重指数、职业、血型、避孕措施及原发性痛经为与子宫内膜异位症的发病相关的单因素(P<0.05),最终职业(OR=2.52,95%CI:1.28～4.94)、血型(OR=2.46,95%CI:1.13～5.36)、妊娠次数(OR=0.78,95%CI:0.65～0.93)、剖宫产史(OR=2.39,95%CI:1.07～5.38)、原发性痛经(OR=3.49,95%CI:1.81～6.73)5个因素进入多因素回归模型(P<0.05)。结论:从事脑力劳动、A型血、剖宫产史及原发性痛经为经手术证实子宫内膜异位症的主要危险因素,而妊娠次数多为保护因素。

Objective：To explore the related risk factors of endometriosis in the patients undergoing gynecological operation. Methods：A total of 99 patients who were confirmed with benign diseases（except endometriosis） by gynecological operation were selected as control group,and 95 patients with endometriosis were selected as case group,the patients in the two groups were compared and analyzed retrospectively,and 17 related factors were analyzed by univariate unconditional logistic regression analysis and multivariate unconditional logistic regression analysis. Results：The times of pregnancy and delivery,the times of artificial abortion,body mass index,occupation,blood type,contraceptive measures,and primary dysmenorrhea were the single factors related to the occurrence of endometriosis（P0.05）.Five factors including the final profession（OR=2.52,95%CI： 1.28~4.94）,blood type（OR=2.46,95%CI： 1.13~5.36）,the times of pregnancy（OR=0.78,95%CI： 0.65~0.93）,history of cesarean section（OR=2.39,95%CI： 1.07~5.38）,and primary dysmenorrhea entered multivariate regression model（P0.05）. Conclusion：Engaging in brainwork,A blood type,history of cesarean section,and primary dysmenorrhea are the main risk factors of endometriosis confirmed by gynecological operation,while the times of pregnancy is a protective factor.