摘要
目的:探讨滋阴活血类中药治疗女性黄褐斑的临床疗效。方法:采用口服、对照、随机分组,将220例黄褐斑患者随机分为2组,治疗组110例,采用纯中药桃红四物合六味地黄汤加减(桃仁12 g,红花12 g,当归20 g,川芎15 g,白芷9 g,熟地黄15 g,山茱萸12 g,山药15 g,白茯苓15 g,僵蚕15 g,赤芍9 g,牡丹皮9 g,益母草15 g,女贞子12 g等)治疗。配合外用3%氢醌霜,2次/d。对照组110例,采用口服维生素C 0.3 g,3次/d,口服维生素E 0.2 g,2次/d治疗,外用药同中药组。2组患者均连续治疗2个月,采用评分法比较临床疗效。结果:治疗组患者基本治愈37例,显效41例,好转25例,无效7例,总有效率为93.6%,对照组基本治愈17例,显效24例,好转21例,无效48例,总有效率为56.4%,2组比较,差异有统计学意义(P<0.05),治疗组疗效明显优于对照组。结论:滋阴活血类中药治疗黄褐斑疗效显著,是治疗黄褐斑的有效方药。
Objective:To observe the clinical efficiency of traditional Chinese medicine with activating blood circulation and norishing Yin in treatment of female chloasma.Method: Two hundred and twenty patients were randomly divided into control group and the treatment group.110 patients in treatment group was treated by Taohong Siwu and Liuwei Dihuang decoction with 3% topical hydroquinone cream;110 cases in control group were treated by western medicine vitamin C and E.with 3% topical hydroquinone cream.Treatment lasted 2 months.Result: The cure rate in treatment group was 37 cases,markedly effective was 41 cases,improved 25 cases,in effective 7 cases,The total effective rate in was 93.6% and 56.4%,in treatment and control group,respectively.There was significant difference between the two groups.Conclusion: Traditional Chinese medicine treatment with activating blood circulation and norishing Yin in treatment of female chloasma is an effective prescription.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第2期222-224,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
华北煤炭医学院硕士启动基金项目(BS05050)
关键词
桃红四物合六味地黄汤
黄褐斑
临床观察
Taohong Siwu together Liuwei Dihuang decoction
treatment of melasma
clinical observation