中药治疗恶性肿瘤骨转移疼痛临床应用概述

Clinical Application of Traditional Chinese Medicines for Osseous Metastasis Pain of Malignant Tumor

癌性疼痛是肿瘤最为常见的临床症状之一,也是恶性肿瘤骨转移患者最常见、最早出现、最痛苦的症状之一。近年来以辨病辨证相结合,采用中药内服、外用、针灸等方法,对恶性肿瘤骨转移疼痛的临床研究有不少进展,有些治疗方案取得了较满意的疗效,且具有标本兼治、副作用小,价格低廉等优点。临床研究应强调多中心、随机双盲、大样本、设立合理对照组,规范癌性疼痛疗效判定标准,同时重视临床受益指标的评估;重视中药制剂的质量标准控制和有效成分的研究等是今后中药治疗恶性肿瘤骨转移疼痛研究中亟待解决的问题和努力方向。

Objective：Cancerous pain is one of the most frequently appeared symptoms.It is also the common,early and painful symptom in patients with osseous metastasis.In recent years,by combination of syndrome differentiation and disease differentiation,and by the combination of traditional internal therapy with external therapy,there are significant progresses in the clinical research on treatment of cancerous pain induced by malignant metastasis.Some of the therapeutic approaches have gained satisfactory efficacy,with advantages of treating both the principal and the secondary aspects of a disease,less side effects and lower cost.Clinical research emphasizes multi-centered,randomized,double blind,sufficient large sampling,reasonably established control group,standardized evaluation criteria for cancerous pain.Meanwhile,attentions should be paid to the evaluation parameters for clinical benefits,the quality control of medicinal preparations,and the research on the effective components responsible for the efficacy.These issues are goals and the problems should be reached and solved in the near future.