高分辨率数字染色内镜在筛查早期微小结直肠病变中的应用价值

Detect small early colorectal lesions by i-scan endoscopy

目的探讨进行高分辨率数字染色内镜筛查大肠癌前病变的价值。方法127例患者按年龄随机分为2组，分别行普通结肠镜、高分辨率数字染色内镜检查，由后者预判病变病理性质，并与组织病理学相比较。结果普通结肠镜检查64例发现微小病变84个，高分辨率数字染色内镜检查63例患者，单独用高分辨率发现微小病变147个，加用电子染色后共发现微小病变259个，其中包括102个平坦型病变。与病理组织学结果比较，高分辨率数字染色内镜判断病变性质的敏感度和特异度分别为80％、100％。结论高分辨率数字染色内镜显著增加微小结直肠病变的检出率，并能较好地区分病变的性质。

Objective To evaluate the efficacy of i-scan endoscopy in detecting small colorectal pre- cancerous lesions. Methods A total of 127 patients were randomized into 2 groups to underwent conven- tional eolonoscopy and i-scan endoscopy respectively. The findings were compared with pathologic examina- tions. Results A total of 84 lesions were detected by conventional endoscopy in 64 patients, while 147 le- sions were found in 63 patients with high resolution detection only, which was increased to 259 with i-scan, including 102 fiat lesions. With respect to histology, adenomatous lesions could be predicted with a high sen- sitivity （80%） and a high specificity （ 100% ） by i-scan endoscopy. Conclusion More small eoloreetal le- sions can be detected by i-scan endoscopy, which can distinguish neoplasm from non-neoplasm eolorectal lesions.