期刊文献+

细胞因子在疟原虫感染中的作用研究进展 被引量:3

下载PDF
导出
摘要 当前,疟疾仍是全球特别是热带和亚热带地区最严重的公共健康问题之一,迫切需要采取有效措施来应对,其中,疟疾疫苗是主动保护易感人群的重要工具,但至今效果显著者仍如凤毛,其根本在于对疟疾免疫机理揭示不足。
作者 王珊珊 董莹
出处 《中国人兽共患病学报》 CAS CSCD 北大核心 2012年第1期84-87,共4页 Chinese Journal of Zoonoses
  • 相关文献

参考文献32

  • 1Robinson LJ, D'Ombrain MC, Stanisic DI,et al. Cellular tumor necrosis factor, gamma interferon, and interleukin 6 responses as correlates of immunity and risk of clinical plasmodium falciparum malaria in children from Papua New Guinea[J]. Infection and Immunity,2009,77(70) : 3033-3043.
  • 2Luty AJ,Perkins DJ,Lell B,et al. Low interleukin 12 activity in severe plasmodium falciparum malaria[J]. Infection and Immuni- ty, 2000,68(7) : 3909-3915.
  • 3Ong'echa JM , Remo AM, Kristoff J, et al. Increased circulating interleukin (IL)-23 in children with malarial anemia: In vivo and in vitro relationship with co regulatory cytokines IL-12 and IL-10 [J]. Clin Immunol, 2008,126(2) :211-221.
  • 4Malaguarnera L,Imbesi RM,Pignatelli S ,et al. Increased levels of interleukin-12 in Plasmodium Ialciparum malaria: correlation with the severity of disease[J]. Parasite Immunology, 2002,24: 387-389.
  • 5Perkins DJ,Weinberg JB, Kremsner PG. Peter and transforming growth factor betal in severe childhood malaria: relationship of cytokine balance with disease severity[J]. J Infect Dis, 2000,182 : 988-992.
  • 6Musumeci M, Malaguarnera L, Simpore J ,et al. Modulation of immune response in plasmodium falciparum malaria: role of IL- 12,IL-18 and TGF-b[J]. Cytokine,2003,21(4) : 172-178.
  • 7Chaiyaroj SC, Rutta AS, Muenthaisong K,et al. Reduced levels of transforming growth factor 1, interleukin-12 and increased mi- gration inhibitory factor are associated with severe malaria [J]. Acta Trop,2004,89(3) :319-327.
  • 8姜素华,唐慧,邢建新.IL-12在约氏疟原虫感染中作用的初步实验研究[J].农垦医学,2008,30(5):360-362. 被引量:4
  • 9郑伟,刘军,冯辉,韩路,武静静,曹雅明.约氏疟原虫感染早期易感和抵抗小鼠树突状细胞细胞因子的分泌特点[J].中国医科大学学报,2009,38(3):200-202. 被引量:2
  • 10Mohan K, Stevenson MM. Dyserythropoiesis and severe anae- mia associated with malaria correlate with deficient interleukin 12 production[J]. British Journal of Haematology, 1998,103 (4) :942-949.

二级参考文献33

  • 1Ing R,Segura M,Thawani N,et al. Interaction of mouse dendritic cells and malaria-infected erythrocytes: uptake,maturation,and antigen presentation[ J ]. J Immunol, 2006,176( 1 ): 441-450.
  • 2Ocana-Morgner C,Wong KA,Legal F,et al. Role of TGF-β and PGE2 in T cell responses during Plasmodium yoelii infection[ J ].Eur J Immunol,2007,37(6): 1562-1574.
  • 3D'Keeffe M, Hochrein H, Vremec D, et al. Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8^+ dendritic cells only after microbial stimu lus[J]. J Exp Med,2002, 196( 10): 1307-1319.
  • 4Urban BC,Ing R, Stevenson MM. Early interactions between blood-stage Plasmodium parasites and the immune system[J ]. Curr Top Microbiol Immunol, 2005,297 : 25-70.
  • 5Wu Y,Wang QH,Zheng L,et al. Plasmodium yoelii: distinct CD4 (+)CD25 (+) regulatory T cell responses during the early stages of infection in susceptible and resistant mice [J ]. Exp Parasitol,2007,115 (3): 301-304.
  • 6Su Z,Stevenson MM. IL-12 is required for antibody-mediated protective immunity against blood-stage Plasmodium chabaudi AS malaria infection in mice [J ]. J Immunol, 2002,168( 3 ) : 1348-1355.
  • 7Stevenson MM,Tam MF,Wolf SF,et al. IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-αand occurs via a nitric oxide-dependent mechanism[ J ]. J Immunol, 1995,155( 5 ) : 2545-2556.
  • 8Hunter RL, Kidd MR, Olsen MR, et al. Induction of long lasting immunity to Plasmodium yoelii malaria with whole blood-stage antigens and copolymer adjuvants[J]. J Immunol,1995,154:1762-1769.
  • 9苏燎原 刘克良 刘芬菊.ConA 诱导淋巴细胞功能研究[J].中华微生物学和免疫学杂志,1986,6(2):71-75.
  • 10Gately MK, Desai BB, Wditzky AG, et al. Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)[J]. J Immunol,1991,147: 874-882.

共引文献6

同被引文献55

引证文献3

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部