摘要
目的探讨2型糖尿病患者大血管病变与尿微量白蛋白(mAlb)水平的关系。方法将我院2010年1～5月收治的2型糖尿病118例,根据有无颈动脉内膜中层厚度(IMT)增厚分为IMT正常组60例,IMT增厚组52例;选取同期健康体检58例为正常对照组。分别测定3组mAlb,颈动脉超声检测IMT,并分析mAlb与IMT的相关性。结果 ITM正常组mAlb阳性率为70.0%,ITM增厚组mAlb阳性率为84.5%,均高于正常对照组,差异有统计学意义(P<0.05)。ITM增厚组mAlb水平及阳性率高于ITM正常组,且mAlb水平与IMT呈正相关(r=0.215,P<0.05)。结论 2型糖尿病患者的IMT与mAlb水平密切相关,mAlb水平可用于糖尿病大血管病变早期风险的预测。
Objective To investigate the association of microalbum innria （mAlb） with macrovascular atherosclerosis in type 2 diabetic patients. Methods Patients were divided into 3 groups ： group A （T2DM） （ n = 60）, group B （ T2DM ＋ MT） （ n = 52）, group C, the control group（n = 58）. mAlb and arteria carotis intina-media thickness（IMT）were determined in these patients. The relationship of mAlb with carotid arterial IMT was statistically analyzed. Results The mAlb in group A （ 70. 0% ） and B （84. 5% ） was significantly higher than that in groups C（P 〈0.05）. The mAlb in group B was significantly higher than that in group A. 3, significant positive correlation was noted between mAlb and carotid artery IMT （r =0.215, P〈0.05）. Conclusion Macrovascular atherosclerosis in type 2 diabetic patients is significantly correlated to mAlb, which can be used to predict macrovascular atherosclerosis in type 2 diabetic patients.
出处
《临床误诊误治》
2012年第1期74-76,共3页
Clinical Misdiagnosis & Mistherapy
基金
全军医学科学技术研究"十一五"课题(06MA067)
关键词
糖尿病
2型
尿微量白蛋白
颈动脉内膜中层厚度
糖尿病血管病变
Type 2 diabetes mellitus
Microalbum inuria
Carotid artery intina-media thickness
Diabetic angiopathies
