331例儿童血铅水平及微量元素检测的结果分析

Analysis of detection results on blood lead level and microelements contents of 331 children

目的通过对儿童末梢血中铅含量及微量元素的检测,了解儿童血铅水平及钙、铁、锌等微量元素的综合水平,并对由此而引起的临床表现进行探讨。方法 331例标本取材自沈阳市皇姑区妇幼保健所,分为3个年龄组,分别采用北京博晖电子科技发展有限公司所生产的BH-5100微量元素分析仪和BH2100铅镉分析仪检测末梢血中3种微量元素的含量及静脉血中的铅含量。结果 3种微量元素缺乏情况和血铅水平在性别上差异无统计学意义(P>0.05)。3个年龄段的儿童不同程度地缺乏各种微量元素,其中以缺锌最多(35%),其次是缺铁(22.4%)和缺钙(5.1%)。本研究中未发现铅中毒,但结果显示随着年龄的上升血铅含量有所增加。结论 3个年龄段的儿童不同程度地缺乏各种微量元素,而血铅水平随年龄的增长而升高。提示应注意儿童膳食结构的改变,强调饮食合理,营养平衡,做到早期干预、早期治疗。

Objective To understand the levels of blood lead,calcium,iron,zinc and other trace elements in children＇s peripheral blood through detecting the lead content and trace elements in children＇s venous blood and to investigate their clinical manifestations.Methods 331 samples were collected from the Women and Children Hospital of Huanggu district of Shenyang and randomly divided into three age groups.Three kinds of trace element and plumbum level in blood were detected by type BH5100 and BH2100 atomic absorption spectrometry,respectively.Results There was no significant difference of the microelement contents between boys and girls（P0.05）.Each kind of microelement was deficient to different degree in three age groups,in which zinc was at most deficient,accounting for 35%;followed by iron deficiency（22.4%） and calcium deficiency（5.1%）.In this research,lead poisoning was not found,but the results showed that blood lead levels were increased with age growing.Conclusion Each kind of microelement was deficient to different degree in three age groups and blood lead levels was increased with age growing.Changes in dietary patterns of children should be paid attention to.Parents should emphasize reasonable diet and nutritional balance.