鲍氏不动杆菌临床感染分布及药敏分析

Clinical distribution and drug susceptibility of Acinetobacter baumanniiinfections

目的了解某院近3年鲍氏不动杆菌(ABA)临床感染分布和耐药性。方法应用法国生物梅里埃公司VITEK-2系统,对688株ABA进行细菌培养鉴定及药敏分析。结果 2007年1月-2009年12月共分离ABA688株,其中80.96%来自痰标本;ABA科室分布主要为ICU和儿科;该菌对阿米卡星敏感率最高为83.66%,对美罗培南、美洛西林和亚胺培南的敏感率分别为40.31%、40.30%和38.44%,对头孢吡肟、头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、磺胺甲噁唑/甲氧苄啶、庆大霉素、环丙沙星和左氧氟沙星的敏感率均<35.0%。结论 ABA感染以ICU和儿科最常见,其耐药现状严重。

OBJECTIVE To investigate the distribution and susceptibility profile of clinical isolated Acinetobacter baumannii（ABA） during the past 3 years.METHODS Species identification and antibiotic susceptibilities of 688 strains of Acinetobacter baumannii were determined by VITEK-2 system manufactured by BioMerieux,France.RESULTS A total of 688 strains were isolated during the period from Jan.2007 to Dec.2009,80.96% of which were isolated from sputum specimens.ABA strains were mainly isolated from ICU and pediatrics patients.83.66% of them were susceptible to amikacin.The susceptible rates to meropenem,mezlocillin and imipenem were 40.31%,40.30% and 38.44%,respectively.The susceptible rates to cefepime,cefoperazone/sulbactam,piperacillin/tazobactam,trimethoprim/sulfamethoxazole,gentamicin,ciprofloxacin and levofloxacin were under 35.0%.CONCLUSION The infection of ABA is most common in ICU and pediatrics patients.The resistance is becoming more and more serious.