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单倍体相合造血干细胞移植后细胞免疫重建的动力学的临床研究 被引量：2

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摘要 异基因造血干细胞移植（allo-HSCT）属于造血免疫细胞移植,NK细胞是HSCT后最早开始恢复的淋巴细胞亚群.NK细胞受体分子（KIR）在HSCT中与移植物抗宿主病（GVHD）发生以及与移植后复发的关系引人注目[1].异基因供者移植物中的CD4＋ CD25＋细胞群（Tmg）细胞比例与GVHD发生有关[2-3].我们前期的实验研究发现供者未成熟DC细胞可以防止骨髓移植后GVHD发生而不减弱移植物抗白血病（GVL）效应[4].
作者 段连宁 闫红敏 薛梅 丁丽 刘静 朱玲 葛淑静 王恒湘 纪树荃
机构地区 空军总医院血液科
出处 《中华血液学杂志》 CAS CSCD 北大核心 2012年第1期53-55,共3页 Chinese Journal of Hematology
基金 国家自然科学基金（30170395）
关键词 异基因造血干细胞移植 细胞免疫重建 移植后复发 单倍体相合 临床研究 移植物抗宿主病 动力学 移植物抗白血病
分类号 R457 [医药卫生—治疗学]
  • 相关文献

参考文献13

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二级参考文献12

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共引文献9

同被引文献25

  • 1蒋盼,汪华.自然杀伤细胞表面受体NKp46的研究进展[J].中华临床医师杂志（电子版）,2011,5(22):6711-6714. 被引量：5
  • 2于津浦,曹水,辛宁,安秀梅,齐静,任秀宝.低剂量氟达拉滨、环磷酰胺联合供者NK细胞作为非清髓性预处理用于小鼠单倍相合造血干细胞移植[J].中国实验血液学杂志,2007,15(5):1013-1018. 被引量：2
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引证文献2

中华血液学杂志
2012年 第1期

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