催乳素与自然流产相关性的研究进展

Research advances in the relationship between prolactin and spontaneous abortion

自然流产是常见的妊娠疾病之一,在已婚妇女中的发病率为1%～5%,是困扰生育期妇女的一个严重问题。引起自然流产的因素很多,其中由内分泌异常所导致的自然流产是能够检测出病因并可以进行积极治疗的。催乳素是参与生殖调节的重要内分泌激素,在早孕期对着床和维持妊娠起着重要作用。催乳素水平的异常与自然流产密切相关,但二者之间的关系尚待深入研究,本文分析近年来研究催乳素与自然流产的文献,对两者的相关性进行综述。

Spontaneous abortion is one of the most common gestational conditions, with the morbidity of 1% to 5% in married women. It is a serious problem troubling women at the reproductive age. There are many factors causing spontaneous abortion, among them, spontaneous abortion resulting from endocrine abnormalities can be detected and treated. Prolactin is a major endocrine hormone participating in reproductive regulation and playing an important role in early pregnancy implantation and pregnancy maintenance. When there are unusual levels it is closely related to spontaneous abortion, leading to a necessity to further study the relationship between them. International and domestic research developments in recent years about the correlation between prolactin and spontaneous abortion are discussed in this paper.