变应性鼻炎特异性免疫治疗疗效和依从性分析

Efficacy and compliance of specific immunotherapy in allergic rhinitis

目的:探讨变应性鼻炎患者特异性免疫治疗的疗效、安全性及依从性。方法:对采用安脱达尘螨疫苗制剂进行免疫治疗的280例变应性鼻炎患者,通过等级评分观察其症状、体征及疗效。结果:对治疗1年以上患者的症状、体征积分等进行统计,治疗16周、6个月、1年后的总有效率分别为86.8%、70.4%、62.5%;280例患者治疗1年后停止治疗74例,依从率为73.6%。结论:对变应性鼻炎患者规范的特异性免疫治疗是一种安全性高且有效的对因治疗方法,在变应性鼻炎的综合治疗中值得重视和推广,同时要加强患者健康教育来提高治疗依从性。

To evaluate the efficacy, safety and compliance of specific immunotherapy in allergic rhi- nitis. Method： Two hundred and eighty cases with allergic rhinitis were undertaken immunotherapy, and then were observed its symptoms, signs and treatment by graded score. Result：otal effective rate was 86. 80//oo, 70. 4%, 62.5% at 16 week, 6 months and 1 year after treatment. Of 280 patients treated, 74 patients stopped treatment after one year, compliance rate was 73.60/6o. Conclusion： Specific immunotherapy is a safe and effective treatment methods for allergic rhinitis and worthy of attention and promotion, while strengthening the health education is needed to improve treatment compliance of patients.