高压氧治疗重型脑外伤觉醒功能障碍的疗效观察

Observation on the Efficacy of Hyperbaric Oxygen for the Treatment of Arousal Impairment of Severe Craniocerebral Injury

[目的]探讨高压氧对重型脑外伤患者脑觉醒的早期康复治疗效果.[方法]将122例重型脑外伤患者随机分为观察组和对照组,每组61例.在神经外科常规治疗护理基础上,对照组给予针刺治疗（穴取水沟、内关,三阴交为主）,观察组在对照组基础上加用高压氧治疗,30 d后比较两组的昏迷转清醒率、苏醒时间及临床疗效.[结果]观察组患者昏迷转清醒率为83.6%（51/61）,高于对照组的59.0%（36/61）,且两组相比较差异有显著性（P＜0.01）,观察组苏醒时间较对照组明显缩短（P＜0.01）,临床疗效亦明显优于对照组（P＜0.01）.[结论]在常规治疗和针刺治疗的基础上,早期高压氧干预能够加快重型脑外伤患者觉醒功能的恢复.

[Objective]To explore the early rehabilitation effect of hyperbaric oxygenation（HBO） on brain arousal in severe craniocerebral injury. [Methods] Totally 122 cases of severe craniocerebral injury were randomly divided into the observation group and the control group with 61 cases in each group. Based on the conventional nursing care in neurosurgery, the control group was given acupuncture treatment（mainly the points of shuigou, Neiguan and Sanyinjiao）. The observation group additionally received HBO on the basis of the treatment of the control group. Thirty days later, the arousal rate from coma, arousal time and clinical efficacy were compared between two groups. [Results]The arousal rate from coma was 83.6% （51/61） in observation group, which was higher than that in control group（59.0 % ）, and there was significant difference between two groups（ P 〈0.01）. The arousal time in observation group was shortened remarkably as compared with control group（ P 〈0. 01）, and the clinical efficacy was superior apparently to that in control group （ P 〈0.01）. [Conclusion] On the basis of conventional treatment and acupuncture therapy, HBO intervention at early stage can accelerate the recovery of brain arousal function in patients with severe craniocerebral injury.