冷应激下民猪黑素皮质素受体基因的表达变化

Gene Expression Change of Pig MC3R at Cold Stress

黑素皮质素受体3(melanocortins 3 receptors,MC3R)是G-蛋白耦联受体超家族的成员之一。研究采用Real-time PCR的方法,对冷应激下民猪腿肌内MC3R基因的表达变化情况进行了研究。结果表明,冷应激下,MC3R基因的表达出现了显著地上升(P<0.05)。据此推测,民猪很可能是通过上调MC3R基因的表达来增加能量消耗而抵御寒冷气候的。

Melanocortins 3 receptors（MC3R） is a member of the G-protein-coupled receptor super family.In this study,Real-time PCR method was used to detect the expression level of MC3R in leg muscle of Min pig under cold stress condition.The results showed that under cold stress condition MC3R gene expression increased significantly（P〈0.05）.To infer,Min pig is likely to increase the expression of MC3R gene to improve energy consumption to withstand the cold climate.The results show that under cold stress,MC3R gene expression appeared significantly increased（P〈0.05）.It presumed that Min pig is likely to increase the expression of MC3R gene to increase energy consumption to resist cold climate.