长期口服小剂量阿司匹林对血清前列腺特异性抗原的影响

The effect of long term oral taking low dose aspirin on serum prostatic specific antigen

目的观察长期小剂量口服阿司匹林对血清前列腺特异性抗原(PSA)的检测是否产生影响。方法选择2008年6月至2010年10月,来本院泌尿外科就诊患者共182例,其中因自身心血管等疾病需长期(超过3个月)小剂量口服阿司匹林的患者54例作为阿司匹林组,128例未服用阿司匹林的患者为对照组。观察PSA检测后两组的差异。结果长期小剂量口服阿司匹林,会降低血清PSA的水平,在年龄超过60岁的患者中,表现尤为明显。结论长期口服小剂量阿司匹林会影响血清PSA检测值,需引起临床重视。

Objective To investigate the effect of long term oral taking low dose aspirin on serum prostatic specific antigen（PSA）.Methods From June 2008 to October 2010,182 outpatients were erolled in the study.54 long term oral taking aspirin patients with cardiovascular diseases were used as aspirin group,128 patients were used as control.Serum PSA level was detected.Results Serum PSA level was significantly lower in aspirin group than in control group（P〈0.05）.Conclusion Long term oral taking low dose aspirin can influence serum PSA level.