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血清乳酸脱氢酶测定在肺癌诊疗中的应用 被引量:9

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摘要 目的探讨血清乳酸脱氢酶活性对肺癌的诊疗价值。方法用酶促反应法,连续监测198例肺癌患者血清LDH活性。结果 NSCLC患者各期LDH活性(U/L)分别为:Ⅰ期161.4±24.9,Ⅱ期173.1±24.9,Ⅲa期189.1±32.2,Ⅲb期239.9±103.2,Ⅳ期255.9±109.9;SCLC患者局限期LDH活性(U/L)为189.1±77.2,广泛期为339.2±100.4。肺癌患者血清LDH活性与原发肿块最长径、淋巴结转移(NSCLC)、远处转移(SCLC)呈显著正相关,P值分别为<0.05、<0.01和<0.01。结论 NSCLCⅠ~Ⅳ期及SCLC局限期至广泛期患者血清LDH活性呈逐渐升高趋势,并与原发肿块最长径、淋巴结转移及远处转移相关,血清乳酸脱氢酶活性测定对肺癌的早期诊断、疗效评价和预后监测具有重要价值。
出处 《临床肺科杂志》 2012年第2期362-363,共2页 Journal of Clinical Pulmonary Medicine
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